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Hefei Reachever Import and Export Limited Company

Ondansetron HCl, Antemetic, 146475-23-2 manufacturer / supplier in China, offering Antemetic API Ondansetron HCl (146475-23-2), Maintain Normal Growth and Development Vitamin H (58-85-5), Biotin Maintain Normal Growth and Development Vitamin H Biotin and so on.

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Antemetic API Ondansetron HCl (146475-23-2)

FOB Price: US $20-100 / KG
Min. Order: 1 KG
Min. Order FOB Price
1 KG US $20-100/ KG
Get Latest Price
Port: Shanghai, China
Production Capacity: 5000kgs/Month
Payment Terms: L/C, T/T, D/P, Paypal
Basic Info
  • Model NO.: BP USP EP
  • Certification: SGS
  • Type: Analysis reagent
  • Volatile: Not Volatile
  • Loss on Drying: Nmt 0.5%
  • Transport Package: 25kg/Drum
  • Origin: China(Mainland)
  • Function: Gastrointestinal Agents
  • Grade Standard: Medicine Grade
  • State: Crystalline Powder
  • Assay: 98~102%
  • Trademark: REACHEVER
  • Specification: GSG
Product Description
ANTEMETIC ONDANSETRON HCL

CAS NO 146475-23-2/146844-89-5
MF: C17H19F2N3O3
Standard: BP/EP/USP
ASSAY 98~102%
White or almost white crystalline powder

Slightly soluble in water, very slightly soluble in methanol, practically insoluble in ethano

Test items

Standard

Test results

Description

White or almost white crystalline powder

white crystalline powder

Solubilit

Slightly soluble in water ,very slightly soluble in methanol, practically insoluble in ethano

Complies

Identificatio

IR vs standard

Complies

Test for specific optical rotation

Complies

Appearance of solution

The solution is clear and colorless

Complies

Acidity

Not more than 0.6ml of 0.01M Naoh is required to change the color of  the indicator to pink

0.44ml

Specific optical rotatio

+74.5°~+78.0°

+75.6°

Related substances

ImpurityA:NMT0.1%

0.03%

Impurity B: NMT0.1%

0.05%

Impurity C: NMT0.1%

0.03%

Any other impurity:NMT0.1%

0.05%

Total of other impurities:NMT0.1%

0.06%

Total of impurities:NMT0.3%

0.16%

Impurity D

NMT0.1%

0.01%

Silver

NMT5ppm

<1ppm

Loss on drying

NMT0.5%

  0.19%

Assay

98~102% (dried substance)

99.85%

Bacterial endotoxins

<1.0IU/mg

Complies
Antemetic API Ondansetron HCl (146475-23-2)

USE:
Ondansetron hcl is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic, often following chemotherapy. It affects both peripheral and central nerves. Ondansetron reduces the activity of the vagus nerve, which deactivates the vomiting center in the medulla oblongata, and also blocks serotonin receptors in the chemoreceptor trigger zone. It has little effect on vomiting caused by motion sickness, and does not have any effect on dopamine receptors or muscarinic receptors.  
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